A primer on peroxiredoxin biochemistry

A primer on peroxiredoxin biochemistry.

Peroxiredoxins were not recognized as a family of enzymes until the 1990s but are now known to be the dominant peroxidases in most organisms. Here, the history and fundamental properties of peroxiredoxins are briefly reviewed, with a special focus on describing how an exquisitely tunable balance between fully folded and locally unfolded conformations plays a large role in peroxiredoxin catalyti...

A PRIMER ON FUZZY OPTIMIZATION MODELS AND METHODS

Fuzzy Linear Programming models and methods has been one ofthe most and well studied topics inside the broad area of Soft Computing. Itsapplications as well as practical realizations can be found in all the real worldareas. In this paper a basic introduction to the main models and methods infuzzy mathematical programming, with special emphasis on those developedby the authors, is presented. As ...

Overview on Peroxiredoxin

Peroxiredoxins (Prxs) are a very large and highly conserved family of peroxidases that reduce peroxides, with a conserved cysteine residue, designated the "peroxidatic" Cys (CP) serving as the site of oxidation by peroxides (Hall et al., 2011; Rhee et al., 2012). Peroxides oxidize the CP-SH to cysteine sulfenic acid (CP-SOH), which then reacts with another cysteine residue, named the "resolving...

A Primer on Bioethics

A Primer on Metagenomics

Metagenomics is a discipline that enables the genomic study of uncultured microorganisms. Faster, cheaper sequencing technologies and the ability to sequence uncultured microbes sampled directly from their habitats are expanding and transforming our view of the microbial world. Distilling meaningful information from the millions of new genomic sequences presents a serious challenge to bioinform...